Mapping Cochlear Duct Length to Electrically Evoked Compound Action Potentials in Cochlear Implantation.

Abstract

Objective measurements may assist in indicating cochlear implants and in predicting outcomes of cochlear implantation surgery. Using electrically evoked compound action potentials (ECAP), information about the function of the auditory nerve can be obtained by analyzing responses to electrical stimulation transmitted and derived by the recording electrode. The aim of this study was to determine whether ECAP characteristics differ depending on the stimulated intracochlear region and the size of the cochlea. Retrospective cohort study. University Medical center, tertiary academic referral center. Patients undergoing cochlear implant surgery between 2015 and 2018. Cochlear implantation with FLEXsoft electrode arrays (length 31.5 mm, 12 stimulating channels). The cochlear duct length (CDL) and the cochlear coverage (CC) were measured using a new computed tomography-based software and correlated to the postoperative speech performance. Additionally, ECAP were measured and associated to the CDL. A total of 59 ears of 53 cochlear implant users with a mean age of 63.6 (SD 14.9) years were included. The mean estimated CDL was 35.0 (SD 2.2) mm. The mean CC was 90.3% (SD 5.5%). A total of 4,873 ECAP were measured. A statistically significant, moderate, negative correlation between the ECAP slope and the site of stimulation was found (r = -0.29, 95% confidence interval: -0.32 to -0.27, p < 0.0001). No correlation between the CC and the speech performance was found (r = -0.08, 95% confidence interval: -0.33 to 0.18 p = 0.52). ECAP slopes seem to be a reliable tool to identify the electrode's position inside the cochlea and also showed correlations to the anatomy of the patient. A combination of objective measurements such as anatomical parameters and ECAPs are helpful to assist the postoperative fitting and are promising tools to improve patient care.