MAP 1C is a motor

Abstract

When the protein dynein was discovered to provide the flagellar bending force to axonemal microtubules (MTs) (Gibbons, 1963), “people had jumped to the reasonable hypothesis that dynein was perhaps also involved in other microtubule movements,” recalls Richard Vallee (Columbia University Medical Center, New York, NY). But by the 1980s, no such cytoplasmic motor proteins had been found.