Abstract
It is no secret that proton pump inhibitor (PPI) use is common. Around 10% of the general population in some countries take a PPI. That number can climb up to 25% if we look at older people specifically. For most indications, PPIs are recommended for up to 8 weeks, though some people will need them beyond that period (eg, those with high risk of gastrointestinal bleeding, Barrett's esophagus, severe esophagitis, among other reasons). We know that PPIs are often taken for longer than needed or get started when they were never needed in the first place. Most studies looking at rates of unnecessary PPI use suggest around 50% of PPI users take them without ongoing need. Sometimes people stay on PPIs for years unnecessarily.
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