Abstract

A ready-for-use enteral feeding product was manufactured based on energy standard mixing using hydrolyzed products from local foods (i.e., loin pork, carrot, pumpkin, soybean, rice, and potato). When compared to enteral foods based on defined ingredients, the manufactured product is more cost-effective, appropriately functional and has similar physicochemical properties. Relative protein digestibility for in vitro value was tested by using enzyme pepsin, pH-drop and pH-stat method with three different enzymes. The product was shown to be easily digested with an in vivo digestibility value of 89.7%. Molecule sizes of components in the product ranged from 3.5 to 8.5 kDa, determined by SDS-PAGE, and the average molecular weight was 1.52 kDa, determined by Gel Permeation Chromatography (GPC) method. In terms of nutritional value, the product achieved a caloric density of 1 kcal/mL, dietary fibers of 1.48 g per 100 mL and provided both oligomeric and monomeric forms of protein. In addition, the product has the leucine: isoleucine: valine ratio of 2:1:1, thus facilitating the absorption of the protein. In conclusion, the manufactured enteral feeding product has been shown to be appropriate for providing nutritional support for patients.

Highlights

  • In parallel with the rapid development of nutritional supplements, products for enteral nutrition support have become increasingly common and are widely applied in routine clinical practice, contributing to the reduction of mortality in the treatment of severe patients [1,2,3,4]

  • In most hospitals in Vietnam, the enteral feedings are either blenderized diets prepared by caretakers or formulas unreliably prepared by hospitals from various types of foods such as milk, meat, rice, and vegetables

  • The results revealed that the optimal branched chain amino acids (BCAA) ratio should vary between 1:1:1 and 2:1:1 [41]

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Summary

Introduction

In parallel with the rapid development of nutritional supplements, products for enteral nutrition support have become increasingly common and are widely applied in routine clinical practice, contributing to the reduction of mortality in the treatment of severe patients [1,2,3,4]. Enteral foods are a class of liquid foods fed to patients though a catheter under medical indication and control. Enteral nutrition (EN) is a safe, effective and generally well-tolerated means of administering nutritional therapy to the normally functioning gastrointestinal tract (GI) of patients who are unable to eat or swallow. The increased diversity and popularity of commercial EN formulas has contributed. In order to be used effectively, EN formulas should meet strict requirements.

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