Mannheimia haemolytica pleuropneumonia in goats associated with shipping stress

Paula Augusto Taunde,Franciele Maboni Siqueira,Luciana Sonne,Andréia Vielmo,Fernando Froner Argenta,Bruna Corrêa Lopes,Caroline Pinto De Andrade,Saulo Petinatti Pavarini,David Driemeier,Bianca Santana De Cecco,Ronaldo Michel Bianchi,Gustavo Geraldo Medina Snel,Claudio Severo Lombardo De Barros

doi:10.1590/0103-8478cr20180621

Paula Augusto Taunde, Franciele Maboni Siqueira + Show 11 more

Open Access

https://doi.org/10.1590/0103-8478cr20180621

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Journal: Ciência Rural	Publication Date: Jan 1, 2019
Citations: 17	License type: CC BY 4.0

Affiliation: Universidade Federal do Rio Grande do Sul

Abstract

ABSTRACT: This study described the epidemiological, clinical, pathological and bacteriological aspects of Mannheimia haemolytica pleuropneumonia in goats associated with shipping stress. Forty goats transported from the Northeast to the Southern region of Brazil died during shipment, or 2-3 days after unloading. Clinical signs included dyspnea, mucopurulent nasal discharge, and coughing. All goats were necropsied, and multiple tissues were collected for histopathological analysis and involved agent identifications. All lungs showed pulmonary consolidation, predominantly affecting the cranioventral lobes, in addition to the marked fibrinous pleuritis, pleural thickening, and pleural adhesions, that affected 90% of the goats. Histologically, there was fibrino-suppurative pleuropneumonia characterized by a diffuse neutrophilic infiltrate admixed with fibrin. Non-hemolytic [85% (34/40)] and hemolytic [15% (6/40)] species were obtained in bacteriological culture. Fir Mannheimia spp. was reported in 26 isolates and subsequently confirmed as M. haemolytica (99% identity), after amplification and partial sequencing of the 16S rDNA gene. Stress may trigger the development of bacterial pleuropneumonia in goats, and non-hemolytic strains of M. haemolytica may cause this condition in goats with severe immunosuppression.

Highlights

Respiratory infections are significant causes of death in goats and result a variety of factors, including viruses, bacteria, fungi, parasites, environmental conditions, farming, and host characteristics (MAHU et al, 2015 PONNUSAMY et al, 2017)
M. haemolytica is an opportunistic bacterium that causes pleuropneumonia in ruminants, mainly cattle, and goats are less susceptible they are vulnerable in stressful conditions such as transportation (RAHAL et al, 2014; PONNUSAMY et al, 2017; SINGH et al, 2011)
In eight shipments of goats conducted from June 2016 to December 2017 from Northeast Brazil to Porto Alegre in closed trucks with poor ventilation and hygiene, 40 6–month-old to 4-yearold goats (28 males and 12 females) died due to pleuropneumonia

Summary

Introduction

Respiratory infections are significant causes of death in goats and result a variety of factors, including viruses, bacteria, fungi, parasites, environmental conditions, farming, and host characteristics (MAHU et al, 2015 PONNUSAMY et al, 2017). Bacteria are the main infectious agents in goats with respiratory disease. M. haemolytica is an opportunistic bacterium that causes pleuropneumonia in ruminants, mainly cattle, and goats are less susceptible they are vulnerable in stressful conditions such as transportation (RAHAL et al, 2014; PONNUSAMY et al, 2017; SINGH et al, 2011). M. haemolytica pleuropneumonia can affect goats of all ages (RAHAL et al, 2014; EKONG et al, 2015). The disease can cause high economic losses due to treatment costs, slowdown in weight gain, condemnation of carcasses, and a decrease of meat and milk production (EMIKPE et al, 2010; PONNUSAMY et al, 2017). Diagnosis is based on clinical history, clinical signs, gross and histopathological findings, associated with bacteria

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