Abstract
Stephen J Russell is currently Professor of Medicine and Richard O Jacobson Professor of Molecular Medicine at the Mayo Foundation in Rochester, Minnesota. He obtained his PhD from the University of London, UK and received specialist accreditation in Hematology from the Royal College of Pathologists. In 1998, he took the position of Director of the Molecular Medicine Program at the Mayo Clinic in Rochester, Minnesota. His research interests focus on developing injectable gene therapy vectors for the treatment of disseminated malignancies (particularly multiple myeloma) and demonstrating their efficacy in clinical trials. Laboratory research themes include the engineering of viral membrane glycoproteins, targeting cell–cell fusion and virus entry, pharmacokinetic and pharmacodynamic studies of virus-based therapies, noninvasive monitoring and imaging of viral gene expression in vivo, and radiovirotherapy. His major research thrust is the development of targetable, injectable oncolytic measles viruses for the treatment of multiple myeloma, ovarian cancer, pancreatic cancer and glioma. Vectors derived from retrovirus, lentivirus, adenovirus, alphavirus and nonviral vectors are also studied in his laboratory. te vie w
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