Abstract

The aim of the present study was to analyze and improve the understanding of computed tomography (CT) and positron emission tomography (PET)/CT imaging and the pathological features of solitary thin-walled cavity lung cancer. A total of 16 patients with pathologically confirmed solitary thin-walled cavity lung cancer were included in the present study. All of the patients received CT scans. Among these, two patients underwent an additional PET/CT examination. The CT and PET/CT images were analyzed and a cross-check analysis of the pathological results was conducted. In total, 16 cases of lesions demonstrated thin-walled cavities on the CT images. Among these cases, three presented with an uneven thickening of the cavity walls, 10 cases exhibited wall nodules and three cases presented with compartments in the cavity. The standard uptake value (SUV) of the cavity wall increased in two patients who underwent PET/CT examinations. The 16 cases of lesions were pathologically confirmed as adenocarcinomas. Light microscopy revealed that the tumor cells, which were observed in 12 cases of lesions, had diffused along the inner cavity wall and the tumor cells of four cases had invaded the bronchial wall. Images of the chest that demonstrated a single thin-walled cavity accompanied by uneven thickening of the cavity wall or wall nodules, in addition to an increase in the SUV and compartments in the cavity, indicated potential lung cancer. Valves formed as a result of bronchial wall damage may have led to the cavity.

Highlights

  • Lung cancer is one of the most common types of malignant tumor [1,2] accounting for 22.7% of all cases of malignant tumor [3]

  • There is a lack of knowledge concerning the features of atypical or rare types of lung cancer, these types of cancer are subject to misdiagnosis, missed diagnosis and treatment delay

  • Lung cancer is one of the most common types of malignant tumor and the progression of this type of cancer is associated with the pathological type

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Summary

Introduction

Lung cancer is one of the most common types of malignant tumor [1,2] accounting for 22.7% of all cases of malignant tumor [3]. CT and positron emission tomography (PET) manifestations, as well as the pathological features of these cases, were analyzed to determine their imaging characteristics with the aim of improving the diagnosis rate

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