Abstract
Aim. To evaluate the dynamics of the manifestation of hybrid dysgenesis in the Harwich line observed under the influence of tetracycline and compare the gathered data with the data for the Oregon-R line. Methods. The line of Drosophila melanogaster Harwich was investigated. This line is considered the standard line of the P cytotype. Removal of Wolbachia from the body was implemented using antibiotic tetracycline. The level of hybrid dysgenesis was studied by the method of extracting gonad flies and assessing their condition. Results. A stable and significant increase in the proportion of dysgenic individuals within the Harwich line was recorded after suppression of the internal microflora - including Wolbachia pipientis – by tetracycline. Conclusions. The suppression of the internal microflora of Drosophila melanogaster by tetracycline significantly affects the level of manifestation of hybrid dysgenesis caused by transpositions of the P-element. The data obtained are similar to the results of a similar study of the level of manifestation of hybrid dys-genesis caused by transpositions of hobo MGE. Keywords: mobile genetic elements, hybrid dysgenesis, P-element, Drosophila melanogaster, Wolbachia pipientis.
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