Manganese-Catalyzed Z-Selective Allylation of Indoles with Allenyl Derivatives.

Abstract

Herein, we report a manganese-catalyzed Z-selective hydroarylation of allenyl ethylene carbonates (AECs) under mild conditions. The methodology employs an earth-abundant Mn(I)-catalyst, which shows high functional group tolerance, performed at room temperature, resulting in good-to-excellent yields of the products with very high Z-selectivity. Besides, mechanistic insights reveal the substitution effects of the allenes over the control of Z-selectivity.