Abstract
Manashila, Haratala, and Somala are significant arsenic compounds that are deeply integrated into holistic prac-tices. Among these, Manashila is revered for its versatility and efficacy in treating various ailments. Its wide-spread employment extends to addressing afflictions such as Shwasa-Kasa (respiratory disorders), Agnimandya (digestive weaknesses), Kshaya (emaciation), Anaha (abdominal distention), Jwara (fever), Krimi (parasitic in-fections), Visharoga (poisoning disorders), Raktavikara (blood disorders), and more. The present study offers a comprehensive critical review of Classical literature focusing on Manashila. Numerous classical texts of Rasa Shastra have been meticulously scrutinised to furnish an exhaustive depiction of Manashila, encompassing its Praptisthana (occurrence), Prayaya (synonyms), Vargikarana (classification), Karma (pharmacological proper-ties), Ashuddha Manashila Dosha, its Prativisha (antidote), Shodhana (purification), Marana (incineration), Matra (therapeutic dose), Chikitsiya Prayoga (therapeutic indications), Satvapatana (extraction), along with elu-cidation on artificial methods of Manashila preparation, complemented by insights into Realgar. It is crucial to emphasise that Manashila is exclusively utilised in a purified and detoxified state for internal and external thera-peutic purposes.
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