Abstract
Wound healing is a complex, multi-step process. This process begins immediately after skin damage. The outcome of wound healing depends on the quality of each stage of this process: a normal or pathological scar. Violation of wound healing entails a decrease in the function of scar tissue as well as aesthetic dissatisfaction with the patient. This problem is especially important in aesthetic surgery. Patients who have come for beauty feel frustration, obtaining pathological scars. We have been dealing with the problem of wound healing after plastic surgery for about 10 years. Our approach includes the assessment of the risk of pathological wound healing and the treatment of high-risk patients. The risk assessment includes historical data on wound healing, signs of connective tissue dysfunction (especially patients with connective tissue dysplasia), and genetic polymorphisms of genes responsible for the structure of the components of the extracellular matrix of the skin. In the future, patients with a high risk of pathological scarring can be prescribed treatment after surgery. This article presents a clinical case in which we demonstrate our approach.
Highlights
Introduction iationsWound healing is a complex process aimed at maintaining the integrity of the body [1].Tissue regeneration without scarring is possible only in the fetal period of development; in the postnatal period, healing occurs with scar formation [2]
We describe an example of scar repair following surgery on the arm region
Hypertrophic and keloid scars are a serious problem in aesthetic medicine
Summary
Nikolai N. Potekaev 1 , Olga B. Borzykh 2, * , German V. Medvedev 3 , Marina M. Petrova 2 , Elena I. Karpova 1 , Maria A. Zatolokina 4 , Mustafa Al-Zamil 5 , Olga M. Demina 1 , Ekaterina A. Narodova 2 and Natalia A. Shnayder 2,6, * Citation: Potekaev, N.N.; Borzykh, O.B.; Medvedev, G.V.; Petrova, M.M.; Karpova, E.I.; Zatolokina, M.A.; Al-Zamil, M.; Demina, O.M.; Narodova, E.A.; Shnayder, N.A. High-Risk Patient: A Case Report. Department of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Institute of Personalized Psychiatry and Neurology, Shared Core Facilities, V. M. Bekhterev National Medical
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