Abstract
Although Portugal was one of the first countries eradicating malaria in Europe, the burden of the disease remains high, particularly due to the close relationship with its former african colonies. Due to its adverse effects and higher mortality rate in patients treated with quinine, methanalysis by the Cochrane Group published in June 2012, suggests artesunate as first line therapy in both children and adults with severe malaria, particularly cerebral malaria.
Highlights
Portugal was one of the first countries eradicating malaria in Europe, the burden of the disease remains high, due to the close relationship with its former african colonies
Due to its adverse effects and higher mortality rate in patients treated with quinine, methanalysis by the Cochrane Group published in June 2012, suggests artesunate as first line therapy in both children and adults with severe malaria, cerebral malaria
We selected all cases with confirmed infections by P. falciparum, and registered parameters like age, gender, nationality, country of transmission, severe malaria criteria, indications and contraindications of intravenous quinine, as well as its adverse effects and clinical outcome
Summary
Portugal was one of the first countries eradicating malaria in Europe, the burden of the disease remains high, due to the close relationship with its former african colonies. Due to its adverse effects and higher mortality rate in patients treated with quinine, methanalysis by the Cochrane Group published in June 2012, suggests artesunate as first line therapy in both children and adults with severe malaria, cerebral malaria
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