Abstract

Self-help by means of dietary interventions can help in management of various disorders including rheumatoid arthritis (RA), a debilitating autoimmune disease. Dietary interventions necessitate a widespread appeal for both patients as well as clinicians due to factors including affordability, accessibility, and presence of scientific evidences that demonstrate substantial benefits in reducing disease symptoms such as pain, joint stiffness, swelling, tenderness and associated disability with disease progression. However, there is still an uncertainty among the community about the therapeutic benefits of dietary manipulations for RA. In the present review, we provide an account of different diets and their possible molecular mechanism of actions inducing observed therapeutic benefits for remission and management of RA. We further indicate food that can be a potential aggravating factor for the disease or may help in symptomatic relief. We thereafter summarize and thereby discuss various diets and food which help in reducing levels of inflammatory cytokines in RA patients that may play an effective role in management of RA following proper patient awareness. We thus would like to promote diet management as a tool that can both supplement and complement present treatment strategies for a better patient health and recovery.

Highlights

  • Rheumatoid arthritis (RA) is a systemic, debilitating, chronic inflammatory autoimmune disorder affecting approximately 1% of the world population [1]

  • Ability to walk 2 miles was marginally significant (p = 0.072) and ability to participate in daily activities was more in probiotic group Key note: Adjunctive therapy with probiotics serves effective for rheumatoid arthritis (RA) patients After 4 weeks of elemental diet, the diet group showed significant increase in grip strength (p = 0.008), decrease in Ritchie articular index (RAI) (p = 0.006), and loss of weight as compared to control diet group

  • C-reactive protein (CRP) levels, and RAI but not in HAQ and erythrocyte sedimentation rate (ESR) levels. 72% patients in PPG group and 18% in patients with completely negative SPT (PNG) group suffered from disease allergenic food and for PNG with corn and rice for 12 days. aggravation on food challenge which continued in re-elimination phase

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Summary

Frontiers in Nutrition

Self-help by means of dietary interventions can help in management of various disorders including rheumatoid arthritis (RA), a debilitating autoimmune disease. Dietary interventions necessitate a widespread appeal for both patients as well as clinicians due to factors including affordability, accessibility, and presence of scientific evidences that demonstrate substantial benefits in reducing disease symptoms such as pain, joint stiffness, swelling, tenderness and associated disability with disease progression. We provide an account of different diets and their possible molecular mechanism of actions inducing observed therapeutic benefits for remission and management of RA. We thereafter summarize and thereby discuss various diets and food which help in reducing levels of inflammatory cytokines in RA patients that may play an effective role in management of RA following proper patient awareness.

INTRODUCTION
DIETARY INTERVENTIONS IN RA
SEVEN DAYS FASTING FOLLOWED BY VEGAN DIET
Vegan Diet
Followed which allergenic foods were removed from
Mediterranean Diet
Elemental Diet
Elimination Diet
INDIVIDUAL FOOD ITEMS IN DIET AND THEIR RELEVANCE TO RA
Dietary Fibers and Whole Grains
Essential Fatty Acids
Alcohol Consumption
Spices Herbs Oils Miscellaneous
Findings
CONCLUSION
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