Managing Chronic Health Needs in Child Care and Schools—Fragile X Syndrome

Abstract

Patient Education| 2021 Managing Chronic Health Needs in Child Care and Schools—Fragile X Syndrome Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Share Icon Share Facebook Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Managing Chronic Health Needs in Child Care and Schools—Fragile X Syndrome. Pediatric Patient Education 2021; 10.1542/ppe_document121 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search nav search search input Search input auto suggest search filter All AAP SitesAll PublicationsPediatric Patient Education Search Advanced Search Subjects: Managing Chronic Health Needs in Child Care Fragile X syndrome is an inherited form of intellectual disability that is primarily seen in males. It is the most common form of inherited intellectual disability. Fragile X syndrome is caused by the FMR1 gene on the X chromosome. Females tend to be less affected because they have 2 X chromosomes, and one can compensate for a mutation on the other X chromosome. Males have only 1 X chromosome, so mutational changes are more likely to be expressed. About 1 in 5,000 males born in the United States has fragile X syndrome. Females are less severely and less commonly affected (about 1 in 7,000). Facial features such as a long face, large ears, and a prominent jaw. Moderate to severe intellectual disability. Developmental delay such as gross-motor skill delay, fine-motor skill delay, or speech delay. Infants may have low tone. Behavioral... © 2019 American Academy of Pediatrics. All rights reserved. You do not currently have access to this content.