Abstract
LBA10001 The full, final text of this abstract will be available at abstracts.asco.org at 2:00 PM (EDT) on Friday, June 2, 2017, and in the Annual Meeting Proceedings online supplement to the June 20, 2017, issue of the Journal of Clinical Oncology. Onsite at the Meeting, this abstract will be printed in the Saturday edition of ASCO Daily News.
Highlights
The diagnosis of advanced cancer may trigger enormous distress and the challenge of living meaningfully in the face of progressive disease
Cancer And Living Meaningfully (CALM) participants reported less-severe depressive symptoms than usual care (UC) participants at 3 months (D = 1.09; P = .04; Cohen’s d = 0.23; 95% CI, 0.04 to 2.13) and at 6 months (D = 1.29; P = .02; d = 0.29; 95% CI, 0.24 to 2.35)
Findings suggest that CALM is an effective intervention that provides a systematic approach to alleviating depressive symptoms in patients with advanced cancer and addresses the predictable challenges these patients face
Summary
The diagnosis of advanced cancer may trigger enormous distress and the challenge of living meaningfully in the face of progressive disease. Individuals in this situation face the burden of physical suffering, the threat of dependency and impending mortality, and the difficulty of making treatment decisions that have life-and-death implications while navigating a complex health care system.[1] Early palliative care for such individuals has been shown to produce better outcomes,[2,3,4] but the psychological dimensions of such care are much less systematized than those focused on symptom control and advance care planning. Ground-breaking research on supportiveexpressive therapy has demonstrated positive effects on psychological outcomes in women with metastatic breast cancer.[5,6,7] More recently, three systematic reviews of randomized controlled trials (RCTs) confirmed that psychotherapy is effective in treating depressive states in individuals with advanced cancer, despite methodological limitations in most studies.[8,9,10] Both Dignity Therapy,[11] a legacy-building intervention for those near the Psychological Intervention for Patients With Advanced Cancer
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