Abstract
Aim: To evaluate the effect of a highly potent corticosteroid (dexamethasone) in the treatment of vascular malformation when the location is difficult to reach and complications such as uncontrolled bleeding is predictable in surgery. Background: Vascular malformation is not a common lesion in oral cavity especially in alveolar ridge with extension to the pillar uvula. These lesions arise from capillary or venous malformations with various surgical or non-surgical treatment modalities. Case Description: We performed weekly intralesional injection of dexamethasone in a patient with a vascular malformation in alveolar ridge extending to the lingual side of alveolar ridge and posterior extension to the uvula. Complete resolution of lesion was observed after 6th injection. Conclusion: Intralesional injection of dexamethasone is a potentially curative method to treat oral vascular malformation. Clinical Significance: Injection of dexamethasone is a simple and cost-effective therapy that can be used as a safe treatment for vascular malformations prior to or as a substitute for surgery.
Highlights
In order to evaluate the effectiveness and probable complications of intralesional dexamethasone, this study was performed on a patient with vascular malformation
To best of our knowledge this is the first report to show that vascular malformations can be treated by the use of dexamethasone
The majority of experts believe that many cases of hemangioma in the past have been misdiagnosed and mistreated because the term hemangioma has been used to represent a multitude of vascular entities
Summary
The lesion was red/bluish red in color, measuring 3 × 5 cm in the first visit (Figure 1) and reducing in size on consecutive visits (Figures 1-6). The lesion was prone to bleeding spontaneously or by minor trauma, the diagnosis of a vascular malformation was made clinically. We decided to try dexamethasone injection for the patient. We injected 1 ml of 8 mg/ml dexamethasone by insulin needles into the base of lesions to prevent any leakage and causing less discomfort and pain. The patient received 6 consecutive shots with one-week intervals, and the lesion was examined on days 7, 14, 21, 28, 35, and 42 to evaluate the response (Figures 1-6). The patient was followed for 18 months, and is still symptom free
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