Abstract
A series of 12 infants and young children with complete transposition of the great arteries examined since December, 1967, is reviewed. Five of these children have died and three others have severe pulmonary vascular obstructive disease, rendering at least two of them inoperable. The remaining four, aged up to nine months, are alive and well, and should be suitable for a Mustard-type repair at a later date. Results of balloon atrial septostomy in nine cases have been moderately encouraging; the condition of six patients showed improvement and five are still alive. There has been no morbidity or mortality associated with the procedure. Pulmonary vascular obstructive disease in the presence of ventricular septal defect occurs at a much earlier age In patients with transposition of the great arteries, and we have documented a rise in pulmonary vascular resistance at serial cardiac catheterizations in two patients aged under three years.
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