Abstract

Management of thyroid cancer: United Kingdom National Multidisciplinary Guidelines.

Highlights

  • Thyroid nodules are common, the incidence of palpable nodules in women and men being approximately 5 and 1 per cent, respectively

  • If a nodule is smaller than 10 mm in diameter, Ultrasound scanning (USS) guided fine needle aspiration cytology (FNAC) is not recommended unless clinically suspicious lymph nodes on USS are present. (R)

  • Total thyroidectomy is recommended for patients with tumours greater than 4 cm in diameter or tumours of any size in association with any of the following characteristics: multifocal disease, bilateral disease, extrathyroidal spread, familial disease and those with clinically or radiologically involved nodes and/or distant metastases. (R)

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Summary

Introduction

The incidence of palpable nodules in women and men being approximately 5 and 1 per cent, respectively. With an incidence in the UK of approximately 5 per 100 000 women and 2 per 100 000 men. Long-term prognosis for differentiated thyroid cancer (DTC) is excellent, with survival rates for adults being [92–98] per cent at 10-year follow-up. Treatment and long-term follow-up are essential to achieve and maintain excellent survival rates. Pathophysiology and outcomes, separate guidelines exist for children with DTC,[3] and consensus statements on the various surgical interventions.[4] Patients may initially be seen by a surgeon, endocrinologist, clinical oncologist or nuclear medicine physician, who must be a core member of the thyroid cancer multidisciplinary team (MDT). The goals of treatment for DTC are set out in Box I

BOX I GOALS OF TREATMENT FOR DTC
Peripheral vascularity
Diagnostic of thyroid cancer
GROUP STAGING AND SURVIVAL FOR DIFFERENTIATED THYROID CANCER
TABLE V INITIAL SURGERY FOR PAPILLARY THYROID CARCINOMA
No Yes Only where clinically involved nodes present
Clinical details
Incomplete response
High risk Suppress
Medullary thyroid cancer
Clinical presentation
Stage I Stage II Stage III Stage IV
Findings
Persistent or recurrent MTC
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