Management of the Amniotic Band Syndrome with Cleft Palate: Literature Review and Report of a Case.

José Arturo Garrocho-Rangel,Miguel Ángel Santos-Díaz,Joselín Flores-Velázquez,Amaury Pozos-Guillén,Miguel Ángel Noyola-Frías,Carolina Cortez-Ortega,Socorro Ruiz-Rodríguez

doi:10.1155/2017/7620416

José Arturo Garrocho-Rangel, Miguel Ángel Santos-Díaz + Show 5 more

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https://doi.org/10.1155/2017/7620416

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Abstract

Amniotic Band Syndrome (ABS) is a group of congenital malformations that includes the majority of typical constriction rings and limb and digital amputations, together with major craniofacial, thoracic, and abdominal malformations. The syndrome is caused by early rupture of the amniotic sac. Some of the main oral manifestations include micrognathia, hyperdontia, and cleft lip with or without cleft palate, which is present in 14.6% of patients with this syndrome. The purpose of this report was to describe the clinical characteristics and the oral treatment provided to a 6-month-old male patient affected with ABS with cleft lip and palate.

Highlights

Amniotic Band Syndrome (ABS), known as ADAM, is a rare condition consisting of a broad group of congenital malformations caused mainly by the rupture of the amniotic sac, which produces a series of alterations due to the appearance of fibrous mesodermal amniotic tissue bands [1]
According to recent epidemiologic data, the occurrence of ABS is around 1 in 1,200–15,000 live births and it exhibits no special preference for a specific gender or race [4]; some studies report a slight preference for Afro-Caribbean individuals [2]
The amniotic membranes’ rupture probably took place during the first 45 days of pregnancy, according to the anomalies observed in the patient, such as encephalocele, facial fissure, constriction rings, and toe amputation [18, 20, 21]

Summary

Introduction

Amniotic Band Syndrome (ABS), known as ADAM (acronym for Amniotic Deformity, Adhesions, and Mutilations), is a rare condition consisting of a broad group of congenital malformations caused mainly by the rupture of the amniotic sac, which produces a series of alterations due to the appearance of fibrous mesodermal amniotic tissue bands [1]. The syndrome exhibits different clinical manifestations at birth, such as constriction rings and limb and digital amputations, together with diverse craniofacial malformations and thoracic-abdominal wall anomalies [1, 2]. These defects represent disruptions not occurring along the known lines of embryologic development [2, 3]. Other related manifestations comprising congenital heart defects, renal anomalies, polydactyly, supernumerary nipples, and skin tags [2]

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