Abstract

Status epilepticus is a common pediatric neurological emergency. Management includes prompt administration of appropriately selected anti-seizure medications, identification and treatment of seizure precipitant(s), as well as identification and management of associated systemic complications. This review discusses the definitions, classification, epidemiology and management of status epilepticus and refractory status epilepticus in children.

Highlights

  • IntroductionStatus epilepticus is characterized by prolonged or recurrent seizures without a return to baseline

  • Status epilepticus is characterized by prolonged or recurrent seizures without a return to baseline.It is a common pediatric neurological emergency with an estimated incidence of 18–23 per 100,000 children per year and a mortality of 2%–7% [1]

  • This conceptual definition was pragmatically defined by the International League Against Epilepsy as 30 min of continuous seizure activity, or a series of epileptic seizures during which function is not regained between ictal events in a longer than 30 min period [3]

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Summary

Introduction

Status epilepticus is characterized by prolonged or recurrent seizures without a return to baseline. Management includes prompt administration of appropriately selected anti-seizure medications, identification and management of any seizure precipitant(s), as well as identification and management of associated systemic complications

Definitions and Classification
Medical Management and Stabilization
Diagnostics
Management of Status Epilepticus
Management of Refractory Status Epilepticus
Findings
Conclusions
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