Abstract
Primary hyperparathyroidism (PHPT) is a common condition, affecting approximately 1% of the general population. In women of childbearing age, the correct diagnosis and management is particularly important since PHPT is associated with miscarriage, pre-eclampsia, intrauterine growth restriction, preterm delivery and postpartum neonatal hypocalcaemia. We describe a case series of six women diagnosed with PHPT and their management during pregnancy. We discuss the various diagnostic challenges including interpretation of urine calcium to creatinine clearance ratio during pregnancy, the importance of vitamin D replacement during diagnostic work up and the pros and cons of performing surgery during the 2nd trimester of pregnancy.
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