Abstract

Introduction: Priapism is a rare pathology, known since antiquity. Sickle cell disease is the main aetiology in Africa. The aim of our work was to report our experience in its treatment. Material and Methods: This is a prospective, descriptive study carried out at the urology department of the Libreville University Hospital from January 2018 to December 2020. All sickle cell patients admitted to urology for priapism were included. The parameters studied were socio-demographic, clinical and therapeutic parameters as well as the evolution after treatment. Result: We collected 19 priapisms in sickle cell patients. The average age was 20.9 years with extremes of 4 and 53 years. Fifteen patients were homozygous SS. All patients had stasis priapism. The average consultation time was 22.4 hours. All patients had perioperative medical management combining hyperhydration, analgesia and antibiotic prophylaxis. A vasoactive drug was administered to 13 patients. Sixteen patients had a puncture of the corpus cavernosum. A distal cavernosal-spongiosum shunt under penile block was performed in 6 patients. The outcome was favorable from the outset in 12 cases, marked by complete detumescence of the corpus cavernosum. Partial detumescence was noted in 7 patients with the need for a new puncture of the cavernous body. A complication such as edema of the penis was in only one of our patients. A recurrence was noted in 2 patients. After an average follow-up of 6 months, no sequelae erectile dysfunction was observed. Conclusion: Priapism is a frequent complication among sickle cell patients in Libreville. Medical management associated with a cavernous puncture with administration of vasoactive drugs allows a favourable evolution without after-effects.

Highlights

  • Priapism is a rare pathology, known since antiquity

  • Priapism is a frequent complication among sickle cell patients in Libreville

  • Medical management associated with a cavernous puncture with administration of vasoactive drugs allows a favourable evolution without after-effects

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Summary

Introduction

Priapism is a rare pathology, known since antiquity. Sickle cell disease is the main aetiology in Africa. Conclusion: Priapism is a frequent complication among sickle cell patients in Libreville. Priapism is a rare condition, defined as an abnormally prolonged, often painful and irreducible erection occurring outside of sexual stimulation. It is a pathology known since ancient times. Sickle cell disease is the major haematological cause of priapism in children and adults in Africa. Stasis priapism is thought to result from a blockage of the venous sinuses in the corpus cavernosum by pathological blockage of the detumescence mechanisms, prolonging the erection while the glans or spongy body remains flaccid [1]

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