Abstract

Placental mesenchymal dysplasia (PMD) is a rare placental anomaly. The reported incidence of PMD is 0.02%, although the real frequency might be underestimated. PMD is often misdiagnosed with hydatiform mole (HM) [1–3] because of the similar sonographic findings shared by the two entities [4]. Trophoblastic hyperplasia, which is typical of HM, is always absent in PMD, but consistent diagnostic criteria for PMD are not yet established [5]. PMD is often associated to genetic syndromes. Even in case of a normal karyotype, PMD has been related with intrauterine growth restriction (IUGR) and fetal demise [6].

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