Abstract
Pancreatic necrosis complicates a minority of cases of severe acute pancreatitis but with high morbidity and mortality. Initial management revolves around organ system support, nutritional support, and close surveillance for the development of infectious complications. Enteral feeding is preferred and prophylactic antibiotics are not indicated. Operative management should be delayed until at least 28 days into the disease course. Percutaneous drainage can be used as a temporizing measure. Operative approaches include video-assisted retroperitoneal debdridement, laparoscopic or open transgastric debridement, and open debridement. Endoscopic debridement is an option in select cases.
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