Abstract
Within the realm of systemic lymphoid tumors, those involving the orbit constitute just over 2% of the total number; however, within ocular oncology, lymphoid lesions represent one of the most common primary orbital malignancies. 10 Traditionally, these tumors were characterized histopathologically primarily by morphologic criteria. The advent of immunophenotyping and gene rearrangement studies has greatly expanded our understanding of these tumors and aided in our ability to predict those patients at risk for dissemination of their disease and those patients in whom the disease process is likely to be indolent. This added knowledge has enabled clinicians to design improved treatment plans based on both clinical and pathologic data.
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