Management of Nonmotor Symptoms in Parkinson Disease

Abstract

In this review, non-motor of Parkinson’s disease is described in the context of the progression of the disease. Also briefly discussed are the major treatment strategies. Parkinson’s disease is a slowly progressing neurodegenerative disorder, causing impaired motor function with slow movements, tremor and gait and balance disturbances. A variety of non-motor symptoms are common in Parkinson’s disease, they include various neuropsychiatric manifestations including cognitive dysfunction, hallucinations and other psychotic symptoms, anxiety, apathy, and mood disorders such as depression. (Seppi K, Ray Chaudhuri K, Coelho M, Fox SH, Katzenschlager R, Perez Lloret S, Weintraub D & Sampaio C, 2019) Disorders of sleep and wakefulness are common, including insomnia, parasomnias, restless legs syndrome (RLS), and daytime sleepiness. This article describes the different non-motor symptoms and major treatment strategies.