Abstract
A total of 54 patients with major salivary gland tumor were treated with radiation therapy at The University of Michigan from 1955 to 1975, inclusive. Fifteen had total resection and radiation, 16 had subtotal resection and radiation, and '23 were inoperable and received radiation only. Radiation is given to the primary site with a generous margin and no elective neck irradiation was done. A mean dose of 5720 rads was delivered in about 6 weeks with a 5 treatment per week schedule. Local control rate was different between these groups, 78.4%, 59.8%, 29.9% respectively, as was survival rate at 5 years, 86.7%, 75%, 21.7%. In patients with facial nerve palsy, with combined surgery and radiation, 65.3% local control and 49.7% 5 year survival was obtained. Regional neck node metastpsis was noted in 25,5% and distant metastasis in 24'.1%. Local tumor control was found to be a very important factor in survival: 70,2% survival in patients with local control and 28.7% without. The authors conclude that a combined radical surgery and postoperative radiation would improve the prognosis of these patients with major salivary gland tumors.
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