Abstract
Hypertensive disorders in pregnancy (HDP) is a common and serious clinical syndrome, characterized by hypertension, renal injury, and neurological symptoms in pregnancy, and is a major cause for maternal death. According to 2013 ACOG (American College of Obstetricians and Gynecologists) guideline, HDP is categorized as gestational hypertension, preeclamsia-eclamsia, chronic hypertension, and chronic hypertension complicated with preeclamsia. Patients with blood pressure of ≥160/110 mmHg need antihypertensive therapy of which the first-line drugs are calcium channel blockers and adrenoceptor blocking agents. Renin and angiotensin receptor blockers are contraindicated in the first trimester of pregnancy due to their potential teratogenicity. Patients with mild preeclampsia are suggested to receive expectant management, including antihypertensive medication, symptomatic treatment, and nutritional supportive treatment. HDP has a tendency to spontaneous remission within 12 weeks after delivery. Diagnosis of chronic hypertension is considered if hypertension persists. Renal biopsy should be advised to investigate the underlying chronic kidney disease if proteinuria persists more than six months after delivery. Key words: Pregnancy; Hypertention; Proteinuria; Treatment
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