Abstract
Background – Hyperacidity is one of the most common diseases seen in all ages. Hyperacidity simply means an increased level of acid in the stomach. Unani system of medicine has a treasure of formulations for the treatment of hyperacidity. Methods- Present open labeled,multi-centric, single arm validation was conducted to evaluate the safety and efficacy of Unani pharmacopeial drug Jawarish Amla and Habb-e-Papita in Humuzat-e-Meda (Hyperacidity). Patients with symptoms of hyperacidity like retro-sternal burning,epigastric pain with retro-sternal heaviness,acidic brash,anorexia, nausea and vomiting were included. Patients with known duodenal ulcers, peptic ulcer, gastric surgery gastric carcinoma, Crohn's Diseases, Zollinger Ellison Syndrome, cardiac disorders, respiratory ailments, Diabetes Mellitus, pregnant and lactating females were excluded. Unani formulations,Jawarish Amla 10 g and Habb e Papita 2 tablets were given twice daily after meals for 6 weeks. Clinical & haematological parameters were assessed before and after the treatment to evaluate the safety and efficacy of the drug. Results– No significant changes are observed after 28 days and 84 days during the therapy in the safety profiles of laboratory investigations such as complete haemogram, LFT, KFT. There is significant improvement in the sign and symptoms associated withHumuzat-e-Meda (Hyperacidity). Conclusion- Unani compound formulations Jawarish Amla and Habb-e-Papita are safe and effective in the management ofHumuzat-e-Meda (Hyperacidity).
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