Abstract

Management of end-stage kidney failure in patients with adult polycystic kidney disease

Highlights

  • Adult polycystic kidney disease (APKD) is a genetic inherited disorder characterised by enlarging cysts in the kidney which compress and damage it, resulting over time to kidney enlargement, dysfunction, urological complications and eventual failure

  • The commoner type of APKD is the autosomal dominant variant PKD1 (ADPKD), which affects 90% of patients

  • In the USA, ADPKD is the cause of end-stage renal failure (ESRF) requiring dialysis in 1.4% of Black people and 6.8% of Caucasian people

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Summary

Introduction

Management of end-stage kidney failure in patients with adult polycystic kidney disease Adult polycystic kidney disease (APKD) is a genetic inherited disorder characterised by enlarging cysts in the kidney which compress and damage it, resulting over time to kidney enlargement, dysfunction, urological complications and eventual failure. It is the fourth leading cause of end-stage kidney disease in adults.

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