Abstract
The management of early glottic cancer has evolved significantly over the past decade, with transoral laser (TOL) surgery and radiotherapy emerging as the two most prevalent treatment modalities. The selection of one modality over another continues to generate controversy. With both modalities showing similar efficacy with regard to survival and oncologic outcomes, the selection of one modality over another hinges upon vocal function, quality of life, and cost-effectiveness as the main outcomes of interest. This chapter will begin with a brief overview of the epidemiology and presentation of glottic cancer and will follow with a comprehensive overview of the contemporary literature comparing both treatment modalities.
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