Abstract

Background: Depression is a common and serious disorder that impairs quality of life. Since general practitioners (GP) are considered gatekeepers to secondary care, the choice of interventions offered in primary care can have a significant impact not only on patients’ quality of life, but also on health service demands. Objective: To evaluate the confidence of GPs in diagnosing and managing depression; and, to assess the factors influencing their strategy in treating depression. Methods: A cross-sectional study was carried out among GPs working in the North-East of England, UK. The survey questionnaire consisted of mostly close-ended questions with some allowing for free-text comments (see Appendix 1). The responses obtained were analysed using Microsoft Excel. Results: Among the total of 63 respondents, most GPs were comfortable diagnosing depression. Most would consider combining talking therapies with antidepressants (68.3%) at presentation, followed by referral to talking therapies alone (41.2%). In only 14.3% of cases would antidepressant therapy alone be considered. For those patients non-responsive to initial treatment, 25.4% considered offering a different antidepressant or adjunct medication (such as a sedative, anxiolytic, or beta-blocker), and another 25.4% of GPs considered a combination with another antidepressant. 46.0% of participants were not comfortable prescribing dual antidepressants due to concerns about side effects, lack of experience, paucity of guidelines, and lack of timely access and guidance from the local mental team. Nearly all (98.4%) GP participants would agree to prescribe dual antidepressants on advice of the mental health team with telephone advice being the preferred means of communication in 65.1% of cases. Conclusion: The results of this study can help to develop closer co-operation between primary and secondary care by not only upskilling GPs through various means (educational events, training posts, etc.), but by also creating better communication channels at the interface between those two services. Key words: antidepressants, combination therapy, depression, primary care, primary-secondary care interface

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