Abstract

Since the description of surgery for patent ductus arteriosus in late 1930s, an innumerable number of advances have taken place in the management of congenital heart defects (CHDs). In this review the current status of treatment of seven of the most common acyanotic CHDs was reviewed. The discussion included indications for, and timing of, intervention and methods of intervention. The indications are, by and large, determined by the severity of the lesion. Pressure gradients in obstructive lesions and the magnitude of the shunt in left-to-right shunt lesions are used to assess the severity of the lesion. The timing of intervention is different for each lesion and largely dependent upon when the criteria for indications for intervention were met. Appropriate medical management is necessary in most patients. Trans-catheter methods are preferable in some defects while surgery is a better option in some other defects. The currently available medical, trans-catheter, and surgical methods to treat acyanotic CHD are feasible, safe, and effective.

Highlights

  • Since the description of ductal ligation by Gross and Hubbard [1] in the late 1930s, utilizing digoxin to treat children with congenital heart defects (CHDs) by Gibson [2] and Taussig [3] in mid-1940s, and trans-catheter treatment of tricuspid and pulmonary valve stenosis by Rubio and Limon-Lason [4,5]in the early 1950s, remarkable advances in the management of CHD have occurred

  • Some cardiologists advocate balloon valvuloplasty for lesser gradients, but the author believes that the indications for intervention should remain the same as for surgical intervention and the reasons for such recommendation were detailed in a prior review for the interested reader [19]

  • Since balloon pulmonary valvuloplasty is successful in most cases (Figure 2) [22,27], surgical management is reserved for cases with supravalvular pulmonary artery stenosis, severe valve annular hypoplasia, and dysplastic pulmonary valves

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Summary

Introduction

Since the description of ductal ligation by Gross and Hubbard [1] in the late 1930s, utilizing digoxin to treat children with congenital heart defects (CHDs) by Gibson [2] and Taussig [3] in mid-1940s, and trans-catheter treatment of tricuspid and pulmonary valve stenosis by Rubio and Limon-Lason [4,5]. The author has, from time to time, reviewed the diagnostic and management aspects of CHD [6,7,8,9,10,11,12,13,14,15,16]. The author reviews the current state of the art management aspects of the most common CHD. CHD, a brief description of the defect will be included followed by indications for intervention, timing of intervention, and type of intervention. Due to the extensive nature of the material, discussion of acyanotic CHD will be included in this paper and cyanotic CHD will be discussed in the paper

Pulmonary Stenosis
Indications for Intervention
Timing of Intervention
Type of Intervention
Aortic Stenosis
Coarctation of the Aorta
Atrial Septal Defect
Ostium Secundum ASDs
Ostium Primum ASDs
Sinus Venosus ASDs
Coronary Sinus ASDs
Patent Foramen Ovale
PFOs Associated with Other CHD
Residual PFOs in Previously Treated Complex CHD
PFOs Presumed to be the Seat of Paradoxical Embolism
PFOs in Platypnea-Orthodeoxia Syndrome
PFOs in Other Conditions
Perimembranous VSDs
Supracristal VSDs
Muscular VSDs
Comments
Atrioventricular Septal Defect
Unbalanced AVSDs
Biventricular Repair Along with Bidirectional Glenn Procedure
Biventricular Repair
Conversion from Single-Ventricle to Two-Ventricle Repair
Patent Ductus Arteriosus
Findings
PDA in the Premature
Full Text
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