Abstract

Background: Rapid weight loss following gastric bypass (GBP) predisposes to the development of gallstones, and in those who develop gallstone disease there is a high prevalence of common bile duct stones (CBDS). Furthermore, in these patients, CBDS are difficult to extract due to the altered upper gastrointestinal anatomy following GBP. The aim of the present study was to assess outcome after various management methods applied in the counties of Stockholm and Uppsala, Sweden.Methods: Data from the Swedish Register for Gallstone Surgery and ERCP (GallRiks) and the Swedish Obesity Surgery Register (SoReg) were crossmatched to identify all patients who had undergone gallstone surgery after GBP, where CBDS were found at intraoperative cholangiography, in the Stockholm and Uppsala counties 2009–2013. A retrospective review of patient records was performed for all patients identified.Results: In all, 55 patients were identified. These were managed as follows: expectancy (N = 11); transgastric ERCP (N = 2); laparoscopic choledochotomy (N = 3); open choledochotomy (N = 5); transcystic stone extraction (N = 12); and other approach (N = 13). In nine cases, data on management could not be found. There were nine cases of minor postoperative complication. No retained stones were registered. The operation time was longer for transgastric ERCP (p = 0.002), and the postoperative stay was longer following open and laparoscopic choledochotomy (p < 0.001). There was no statistically significant difference between any of the methods regarding the incidence of postoperative complications (p = 0.098).Discussion: Further development of techniques for managing CBDS discovered in patients undergoing cholecystectomy after previous GBP are needed, as well as more comparative studies with greater statistical power.

Highlights

  • Rapid weight loss following gastric bypass (GBP) predisposes to the development of gallstones, and in those who develop gallstone disease there is a high prevalence of common bile duct stones (CBDS)

  • The prevalence of common bile duct stones encountered at intraoperative cholangiography in the entire cohort of patients undergoing cholecystectomy was 1,661/18,507 (9.0%)

  • The present study, based on data derived from two Swedish population-based registers, does not show any substantial difference in the surgical outcome after the various methods for managing CBDS in patients with a previous history of gastric bypass surgery

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Summary

Introduction

Rapid weight loss following gastric bypass (GBP) predisposes to the development of gallstones, and in those who develop gallstone disease there is a high prevalence of common bile duct stones (CBDS). Several approaches have been suggested for extracting common bile duct stones in patients with a Roux-en-Y limb, including transcystic extraction, laparoscopic cholangiotomy [3], transgastric endoscopic cholangiopancreatography (ERCP) [4,5,6,7,8,9] and overtube-assisted ERCP [9]. Each of these methods are technically complicated, require specific resources, and have certain limitations. At most centers where gallstone surgery is routine, there are usually only one or two methods of management used for CBDS in these patients

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