Abstract
Background: Cervical cancer is the third most common cancer worldwide, and 80% of cases occur in the developing world. A critical component of effective cervical cancer screening programs is the ability to offer women appropriate and effective treatment for cervical intra epithelial neoplasia (CIN). Objectives: This study aimed at assessing the primary experience of management of CIN by Loop Electrosurgical Excision Procedure (LEEP) in a low resource country. Methods: We carried out a descriptive cross sectional study at the Yaoundé General Hospital in Cameroon. Results: Twenty three cases of CIN were treated by LEEP. Mean age of patients was 40.5 ± 9.9 years. Six (26.1%) patients were infected by the Human Immunodeficiency Virus (HIV). LEEP was indicated in 21 (91.30%) cases for CIN2 and CIN3. The mean duration of the surgical procedure was 10 ± 3 minutes. There was one (4.3%) complication (persistent cervical bleeding). Surgical margins were negative for dysplasia or invasive carcinoma in 18 (78.26%) cases and non-applicable in 5 (21.73%) cases (thermal artefacts of margins and cervicitis without CIN). One patient with micro invasive carcinoma on post-operative histology was treated by total hysterectomy. Cervical cytology was normal at 6 months post LEEP for 15 cases out of 16 (93.8%) patients who performed the test. One woman achieved pregnancy and delivered a term baby. Conclusion: Treatment of CIN by LEEP is feasible, safe and effective in our setting.
Highlights
Cervical cancer is the third most common cancer worldwide, and 80% of cases occur in the developing world
Twenty three cases of cervical dysplasia manage by Loop Electrosurgical Excision Procedure (LEEP) in our institution were included in this study
Six cases out of 23 (26.1%) were women infected by the Human Immunodeficiency Virus (HIV).The patients in this study had not realized the test of human papilloma virus (HPV)
Summary
Cervical cancer is the third most common cancer worldwide, and 80% of cases occur in the developing world. Initiation and sustenance of cervical cytology programmes involving the screening of sexually active women annually, or once in every 2 to 5 years, have resulted in a large decline in cervical cancer incidence and mortality over the last 40 to 50 years [2]. The aim of these screening programmes is to detect cervical intra epithelial neoplasia (CIN) and to treat them before they progress to invasive cancer [2].
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