Abstract
Bisphosphonates (BPs) are effective inhibitors of osteoclast mediated bone resorption and thus frequently used in patients with multiple myeloma, osteoporosis, metabolic bone diseases and metastatic bone cancer. Inspite of its benefits, patients are at increased risk of developingBRONJ which adversely affects their quality of life. BPs induced inhibition of osteoclast function may cause defect in jaw bone physiologic remodeling which along with its antiangiogenic properties may predispose the patient to osteonecrosis of jaw. Here, we present a case in which patient with BRONJ who is terminally ill and only conservative management can be given responded favourably to topical medication using custom trays. Keywords: Bronj, Bisphosphonates, Zolendronate, Osteonecrosis, Custom made tray.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: IP International Journal of Periodontology and Implantology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
