Abstract

Rheumatoid Arthritis (R.A) is a chronic, progressive and disabling auto-immune disease that causes chronic inflammation of the joints. It makes life miserable and crippling due to unknown cause, claiming the maximum loss of human working capacity. The polyarticular joint disease has been described in Ayurveda has high resemblance with Rheumatoid arthritis in modern medicine. The disease draws attention for the consideration of research firstly due to the gravity of the problem and secondly due to lack of adverse free modern drugs for the treatment of R.A. Hence the present study has been taken up to see the efficacy of a combination of herbomineral drugs i.e Sunthi, Guggulu and Godanthi bhasma (1:2:1 ratio) on 71 cases of Amavata ( R.A). The study observations showed that the overall treatment response among the cases studied, 10 (15%) cases showed good response, 20 (30%) cases showed fair response, 33 (49%) cases showed mild response and 4 (06%) patients did not show any response and rest 4 cases were dropouts. There was a significant improvement in loss of appetite, anorexia, fever in amavata patients after treatment. Statistical analysis of the mean difference before and after treatment in relief on all the above symptoms except in sub cutaneous nodules and erythrocyte sedimentation rate (ESR), were found highly significant (P<0.0001). It was also observed a definite improvement and subjectively maximum patients had a feeling of well-being. No side effects were reported during and after the treatment.

Highlights

  • Rheumatoid arthritis (R.A) is a chronic multisystem disease of unknown aetiology [1].It is a systemic disorder characterized by chronic inflammatory synovitis involving mainly the peripheral joints [2].The disease apparently has no racial or ethnic discrimination

  • Materials and methods: A total number of 71 established cases of Amavata were selected for this study from the OPD of Regional Research Institute (Ayurveda), Mandi (H.P) during 2001-2004.Clinical, pathological and biochemical investigations carried out as per the proforma and results assessed according to the assessment criteria

  • Rheumatoid arthritis is a complex and variable condition from the point of view of severity. It is usually a “painful nuisance” for which treatment needs to be individualized with optimum dosage of safe, effective and affordable herbomineral drugs i.e rhizomes of Sunthi (Zingiber officinale Roxb.), exudates of Guggulu (Commiphora wighti (Arn.) Bhand.) and Godanthi bhasma (CaSO4, 2H2O) having digestive, analgesic, antipyretic and antiinflammatory properties

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Summary

Introduction

Rheumatoid arthritis (R.A) is a chronic multisystem disease of unknown aetiology [1].It is a systemic disorder characterized by chronic inflammatory synovitis involving mainly the peripheral joints [2].The disease apparently has no racial or ethnic discrimination. The word „Ama‟ means toxic material generated as a un wholesome product in the body, due to weakening of digestive fire. This „Ama‟ is Published online in http://ijam.co.in Venkateshwarlu G et al, Management of Rheumatoid Arthritis carried by „Vayu‟ and travels throughout the body and accumulates in the joints, which is the seat of „Kapha‟. As this process continuous, all the joints are gradually affected, which results in severe pain and swelling in the joints [4]

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