Abstract
Dengue is a viral illness spreads through the bite of Aedes aegypti mosquito leading to a serious health hazard. Dengue induced acute kidney injury is a fatal consequence and there are very few studies reported. Hence early identification of high risk groups is crucial for prevention, to restrict progression and effective treatment of acute kidney injury and to minimise associated morbidity and mortality. The coronavirus disease outbreak has widely spread into a pandemic all over the world. COVID-19 cases have presented with wide spectrum of severity ranging from a mild presentation to severe cases affecting the lungs(ARDS) mainly and rapidly affecting various body organs leading to multiorgan failure. Among these renal involvement is common, the severity of which ranges from mild loss of protein in urine to progressive acute kidney injury requiring renal replacement therapy.
Highlights
In this case report we are reporting the occurrence of acute kidney injury in a patient who was co-infected with dengue and corona virus
Wide spectrum of presentation has been reported ranging from self limiting illness to life threatening severe infections such as dengue haemorrhagic fever (DHF), dengue shock syndrome (DSS) [1]
In addition to mortality caused by DAKI, it leads to increased hospital stay posing a burden to patients and health care system
Summary
Dengue illness is an arthropod transmitted infection prevalent in tropical countries caused by four serotypes (DENV-1, DENV-2, DENV-3, DENV-4), an arbovirus belonging to Flaviviridiae family. The aim of laboratory investigations is to detect the genetic material of dengue virus with the help of various serological or molecular methods out of which ELISA (IgM or IgG) is the most commonly used laboratory test. It detects antibodies against dengue in the blood samples collected during the first six day [3]. The molecular test is useful to detect NS1 antigen of dengue virus, a glycoprotein in the infected cell membranes produced in huge quantities at early stage of the disease. According to WHO circulatory volume should be maintained by judicious administration of crystalloids and out patients can be managed with oral rehydration therapy
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