Abstract
Tissue repair is an essential process that reestablishes tissue integrity and regular function. Nevertheless, different therapeutic factors and clinical conditions may interfere in this process of periapical healing. Long-term success of root canal treatment(RCT) is dependent on sufficient and appropriate cleaning and shaping of the root canal system along with 3 dimensional obturation. This article aims to report a non-surgical and orthograde endodontic retreatment of mandibular right central incisor with a large radicular cyst progression related to endodontic origin in a 51-year-old male. The signs (sinus tract) and symptoms ceased after treatment. Bone formation Complete healing of the periradicular lesion was observed at the two-year follow-up examination. The appropriate diagnosis of periradicular lesion and the treatment of root canal system allowed complete healing of large lesions without endodontic surgery.
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