Abstract

OBJECTIVE: A combination of factors contribute to oocyte quality including, aneuploidy and gene products essential for fertilization and embryonic development. Oocyte quality is a primary contributor to human reproductive failure and has been strongly associated with advanced reproductive age. However, oocyte quality may also play a role in cases of women who present with unexplained infertility and are not considered of advanced reproductive age. This study investigated the protein profiles of MII oocytes from young and mid reproductive age female mice.

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