Abstract
Electrocoagulation in the region of mamillary complex of the hypothalamus induced disturbances in vascular permeability in the rat limb skin. This effect was prevented by pretreatment of the animals with the neurotoxin capsaicin, which indicates participation in the effect of the peptidergic capsaicin-sensitive neurons. The data are discussed in relation to possible mechanisms of central modulation of efferent function of the primary sensory neurons.
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