Abstract
1. 1. Partial purification of malonyl-CoA decarboxylase (EC 4.1.1.9) from rat brain mitochondria and comparison of its size, K m , pH optimum, and immunological crossreactivity showed that the enzyme from the brain is quite similar to that in the other tissues, contrary to previous conclusions. 2. 2. Developmental changes in the activity level of this enzyme in the rat brain mitochondria are reported and a possible function for this enzyme is suggested.
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