Abstract
BackgroundTo study the outcome and experience of using metallic stents in treating patients with malignant ureteral obstruction (MUO).MethodsSeventy-six patients with MUO were assigned to the metallic stent group (MSG) or the ordinary polymer stent group (OPSG) according to the different materials. The success rate of the operation, duration of operation, patency rate serum creatinine values ,postoperative complications and QOL scores were compared between the two groups.ResultsIn the OPSG and MSG, the success rates of the operation were 95.5% and 96.9%, respectively, and the durations of the operation were 20.6 ± 2.2 min and 50.9 ± 10.3 min (P < 0.01), respectively. There was no significant difference between the groups in serum creatinine values at 3 days after the operation (P > 0.05); however, the creatinine values at 3 days after the operation decreased significantly compared with those before the operation (P < 0.01). In the OPSG, there was no significant difference in creatinine values between 3 days and 6 months after operation, while the creatinine values 1 year after operation were increased significantly compared to those at 3 days after the operation (P < 0.05). In the MSG, there was no significant difference among creatinine values at different intervals (P > 0.05). The total rate of post-procedural complication was lower in the MSG than that in the OPSG(P < 0.05). There was no significant difference in the QOL score between the two groups before the operation (P > 0.05); however, the QOL scores at 6 months and 1 year after the operation were higher in the MSG than that in the OPSG(P < 0.05). In the MSG, there was no significant difference in the QOL score between preoperation and 6 months after surgery. Similarly, there was also no difference in the QOL score between 6 months after surgery and 1 year after surgery(P > 0.05). On the contrary, the differences of QOL score in the OPSG group were much significant between disparate time intervals (P < 0.05).ConclusionsFor patients with MUO who require long-term retention of the stent, metallic stents with longer indwelling time are superior to ordinary polymeric stents.
Highlights
Ureteral obstructions secondary to malignant tumour increase each year, mainly due to the following factors
For the ordinary polymer stent group (OPSG), which comprised of 44 patients, a total of 56 stents were indwelled in the first catheterization, and there were 2 failure cases
Duration of operation is shown only for cases with successful surgery bilateral hydronephrosis, there were three cases in the metallic stent group (MSG) where the metallic stent was accepted on the side with better kidney function, whereas ordinary polymeric stent was accepted on the other side
Summary
Ureteral obstructions secondary to malignant tumour increase each year, mainly due to the following factors. Primary tumours infiltrate the ureteral wall; second, tumours or metastatic lesions oppress the ureter; third, the swollen lymphonodus wraps the ureter [1]; fourth, ureter distortion and lumen stenosis occurs due to oedema and retroperitoneal fibrosis after radiotherapy; and fifth, the elasticity of the ureter is weakened after radiotherapy, thereby affecting its peristaltic urine delivery function [2]. Clinical removal of the obstruction and rapid improvement of renal function are the primary principles for treatment In this context, ordinary ureteral stents have poor therapeutic effects and require replacement within a short time, which could lead to secondary trauma; it is necessary to choose methods that maximize the drainage patency and quality of life for the patient, in order to minimize discomfort during stent placement and replacement [3]. To study the outcome and experience of using metallic stents in treating patients with malignant ureteral obstruction (MUO)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
