Abstract
Malignant tumors of the salivary glands are rare malignancies and most of them affect major salivary glands. The aim of this study was to analyze trends in age-standardized incidence rates of major salivary glands tumors among the Belgrade population. Data were obtained from The Serbian Cancer Registry. We analyzed all cases of malignant tumors of major salivary glands registered in Belgrade from January 1st 1999 to December 31st 2010. Joinpoint regression analysis was used to define trends and annual percentage change (APC). A total number of 283 (168 in men and 115 in women) major salivary glands tumors were reported to The Registry during the study period. Age-standardized incidence rate (ASR) for entire period and for both sex was 0.87/100.000 person, 1.13 for men and 0.67 for women. ASR increased with APC of 6.4% in both sexes (p <0.001). Results showed a constant significantly increasing trend of incidence for major salivary glands malignant tumors in the population of the city Belgrade between 1999 and 2010.
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