Abstract
Carcinoma ex pleomorphic adenoma (CPA) is a tumor showing definitive evidence of malignancy in part of a previously benign pleomorphic adenoma (PA). 1 Seifert G Sobin LH Histological Typing of Salivary Gland Tumors. ed 2. World Health Organization, Geneva, Switzerland,1991 Crossref Google Scholar The CPA has been reported to represent 1.4% to 17.5% of all salivary gland tumors 2 Stuteville OH Corley RD Surgical management of tumors of intraoral minor salivary glands. Cancer. 1967; 20: 1578 Crossref PubMed Scopus (50) Google Scholar and from 1.7% to 4.2% of submandibular tumors. 3 Eneroth CM Salivary gland tumors in the parotid gland, and the palate region. Cancer. 1971; 27: 1415 Crossref PubMed Scopus (276) Google Scholar , 4 Thackray AC Lucas RB Tumors of the major salivary glands, in Atlas of Tumor Pathology. Armed Forces Institute of Pathology, Washington, DC1974 Google Scholar We report a case of CPA of the submandibular gland in which malignant transformation was suspected because a size of the lesion and its recent rapid growth.
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