Malignant peripheral nerve sheath tumor (MPNST) – case report and review of literature

Abstract

Malignant peripheral nerve sheath tumors (Mpnsts) are locally invasive soft tissue sarcomas. these tumors constitute up to 10% of all soft tissue sarcomas. they arise from minor or major peripheral nerve branches or sheath of peripheral nerve fibers. they occur with equal frequency in males and females. the majority of malignant peripheral nerve sheath tumors are observed in the extremities. Because of its rarity, this neoplasm is often misdiagnosed. it is characterized by an aggressive behavior and rapid growth. the incidence of malignant peripheral nerve sheath tumor is low with a lifetime risk of 0,001%. the author of this article presented a case of a 76-year-old caucasian woman who was admitted to the department of surgical oncology because of malignant peripheral nerve sheath tumor (Mpnst) which was located on the right side of inguinal and pubis. the progression of disease was very fast. the author performed a literature review on malignant peripheral nerve sheath tumor (Mpnst) diagnosis and treatment.