Abstract
Paragangliomas are neuroendocrine tumors that arise from sympathetic nerve ganglia. They can develop anywhere from the neck to the pelvis, but are most commonly found in the abdomen, particularly at the aortic bifurcation or in the periaortic region. Malignant paragangliomas account for 29–40% of cases. We report a case of 36-year hypertensive female presented with and right flank pain and accelerated hypertension. On evaluation she was diagnosed to have non unctioning kidney due to malignant pelvic paraganglioma with right ureteric encasement. We believe our case is one of the first reported in literature as rare presentation of malignant paraganglioma presenting as nonfunctioning kidney and accelerated hypertension.
Highlights
Paragangliomas are malignant tumors that arise from the extra-adrenal paraganglionic cells of the sympathetic or parasympathetic systems
We present a case of malignant pelvic mass presenting as nonfunctioning kidney and accelerated hypertension
Pheochromocytomas are tumors that arise from chromaffin cells of the adrenal medulla. They are called paraganglioma if chromaffin-cell tumors originate from extra-adrenal sites along the sympathetic and/or the parasympathetic chain [1]
Summary
Paragangliomas are malignant tumors that arise from the extra-adrenal paraganglionic cells of the sympathetic or parasympathetic systems. They can be observed from the base of the skull to the bladder or along the sympathetic ganglionar chain. Retroperitoneal paragangliomas can represent a truesurgical challenge due to their tight relation to largesize vessels. We present a case of malignant pelvic mass presenting as nonfunctioning kidney and accelerated hypertension. Its final histologic diagnosis was paraganglioma that was functional with metastasis to paraaortic nodes
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