Abstract
Chapter 53 discusses malignant osteoid matrix bone tumors and focuses on several types of osteosarcoma, ranging from the most common, conventional osteosarcoma, to secondary osteosarcomas, such as Paget and postradiation sarcomas. Osteosarcoma is the most common primary bone tumor in children and adolescents, and second most frequent primary malignant bone tumor if all age groups are considered. A short discussion on typical radiologic findings with classic examples of various types of osteosarcoma is included. Conventional radiographs show an aggressive lesion with permeative bone destruction, extraosseous soft tissue mass and cortical disruption with periosteal reaction. MRI is useful for assessing tumor extent and skip lesions. Treatment includes surgery and chemotherapy.
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