Abstract
We report four unusual cases of malignant melanoma in which squamous cell carcinoma was strongly considered in the differential diagnosis on routine hematoxylin and eosin-stained sections due to the near absence of melanin and the presence of pseudocarcinomatous hyperplasia. Ultimately, immunohistochemical staining for S-100 protein and keratin established the correct diagnosis of malignant melanoma in all cases.
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