Malignant Melanoma of Anal Canal

Greta Pandey,Nadita Shah,Shankar Bastakoti,Ranjan Raj Bhatta,Ishan Dhungana,Suraj Upreti

doi:10.3126/njc.v5i1.41365

Greta Pandey, Nadita Shah + Show 4 more

Open Access

https://doi.org/10.3126/njc.v5i1.41365

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Abstract

Anal melanoma (AM) is a rare and highly aggressive mucosal melanocytic malignancy. We report a case of 70 year old male presented with chief complaints of anal pain and intermittent rectal bleeding with clinical diagnosis of Polyp or Carcinoma. On histopathology examination malignant melanoma was suggested which was further confirmed by immunohistochemistry (S100 and HMB 45 strongly positive). Anal melanoma is rare neoplastic condition with catastrophic outcome.

Highlights

Anal melanoma (AM) is a rare and highly aggressive mucosal melanocytic malignancy
We report a case of 70 year old male presented in surgical OPD with chief complaints of anal pain and intermittent rectal bleeding especially during defecation
Moore et al, reported the first case of melanoma of anus and rectum in literature in 1857.6 The patients present with pain, anal mass, bleeding per rectum, tenesmus or change in the bowel habits

Summary

Introduction

Anal melanoma (AM) is a rare and highly aggressive mucosal melanocytic malignancy. It comprises approximately 1% of all melanomas and about 0.5–2% of all ano-rectal malignancies.[1]. It comprises approximately 1% of all melanomas and about 0.5–2% of all ano-rectal malignancies.[1] It is the third most common after melanomas of the skin and retina.

Results

Conclusion